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Anti-cancer study of Ni () and Zn ()- chitosan complexes

Authors

  • Beyadir R. Abed
  • Ali O. Mohammed

DOI:

https://doi.org/10.25130/tjps.v27i2.61

Keywords:

chitosan, Nickel, Zinc, breast, ovarian, cell lines

Abstract

Two neutral chitosan polymer complexes with Ni(P) and Zn (P) were prepared and characterized by molar conductivity measurements, IR spectroscopy. The prepared complexes were tested against two types of cancer cell lines {breast cancer (MCF-7) and ovarian cancer (A2780)}. That the Ni-chitosan complex was significantly active then the Zn-chitosan complex with IC50 value is 167.67± 4.6 mg/ml for (MCF-7) and 200.45± 8.23mg/ml for (A2780). Whereas IC50 value of Zn-chitosan complex 189.03± 3.7mg/ml for (MCF-7) and 231.70± 5.25mg/ml for (A2780)

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Published

2022-11-30 — Updated on 2022-12-01

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How to Cite

Beyadir R. Abed, & Ali O. Mohammed. (2022). Anti-cancer study of Ni () and Zn ()- chitosan complexes. Tikrit Journal of Pure Science, 27(2), 11–15. https://doi.org/10.25130/tjps.v27i2.61 (Original work published November 30, 2022)

Issue

Vol. 27 No. 2 (2022)

Section

Articles

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Copyright (c) 2022 Tikrit Journal of Pure Science

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