Anti-cancer study of Ni () and Zn ()- chitosan complexes
DOI:
https://doi.org/10.25130/tjps.v27i2.61Keywords:
chitosan, Nickel, Zinc, breast, ovarian, cell linesAbstract
Two neutral chitosan polymer complexes with Ni(P) and Zn (P) were prepared and characterized by molar conductivity measurements, IR spectroscopy. The prepared complexes were tested against two types of cancer cell lines {breast cancer (MCF-7) and ovarian cancer (A2780)}. That the Ni-chitosan complex was significantly active then the Zn-chitosan complex with IC50 value is 167.67± 4.6 mg/ml for (MCF-7) and 200.45± 8.23mg/ml for (A2780). Whereas IC50 value of Zn-chitosan complex 189.03± 3.7mg/ml for (MCF-7) and 231.70± 5.25mg/ml for (A2780)
Downloads
Published
Versions
- 2022-12-01 (3)
- 2022-12-01 (2)
- 2022-11-30 (1)
How to Cite
Issue
Section
License
Copyright (c) 2022 Tikrit Journal of Pure Science
This work is licensed under a Creative Commons Attribution 4.0 International License.
Tikrit Journal of Pure Science is licensed under the Creative Commons Attribution 4.0 International License, which allows users to copy, create extracts, abstracts, and new works from the article, alter and revise the article, and make commercial use of the article (including reuse and/or resale of the article by commercial entities), provided the user gives appropriate credit (with a link to the formal publication through the relevant DOI), provides a link to the license, indicates if changes were made, and the licensor is not represented as endorsing the use made of the work. The authors hold the copyright for their published work on the Tikrit J. Pure Sci. website, while Tikrit J. Pure Sci. is responsible for appreciate citation of their work, which is released under CC-BY-4.0, enabling the unrestricted use, distribution, and reproduction of an article in any medium, provided that the original work is properly cited.
