Determination of the inhibitory activity of silver nanoparticles against some pathogenic multi-antibiotic resistant bacterial species

Abstract

The study was done to determine the inhibitory effect of silver nanoparticles synthesed by the filamentous fungus Fusarium mangiferae against some multidrugs resistant pathogenic bacteria which were taken from the Central Laboratory of Sulaymaniyah Teaching Hospital.Silver nanoparticles showed their inhibitory effect on the various bacterial species in this study by two methods Wich are the well diffusion method and inhibition growth. Nanoparticles of silver showed inhibitory areas by Well diffusion method against Staphylococcus aureus, Staphylococcus epidermidis, Pseudomonas aeruginosa, and Proteus mirabilis.

The Diameter of inhibition zones of the above mentioned bacteria were (15.25, 20.5, 17.75.16) mm while The method of inhibition of growth had shown that nanoparticles effective against the above bacterial species at concentrations (50, 50, 50, 100)% respectively through the lack of growth of the colonies on the surface of the nutrient agar. Therefore, the use of nanoparticles from some metals is the best solution for the treatment of infectious diseases due to the effective inhibiting properties of these nanoparticles against bacteria without negative side effects.