Synthesis and Characterization of some Pyrazoline derivatives from Chalcones containing azo and ether groups

Authors

  • Ahmed A. ALKazmi
  • Farouq Emam Hawais
  • Yuosra K. Alasadi

DOI:

https://doi.org/10.25130/tjps.v22i9.877

Keywords:

Chalcones, Pyrazoline, Heterocycles

Abstract

A number of 3-(substituted)-5-(2((4-chlorobenzyl)oxy)-5-(m-tolyldizenyl) pheny l) pyrazoline (3a-j) have been synthesized by benzyloxation of hydroxyl group to give the substrate 2-((4-chlorobenzyl)oxy)-5-(m-tolyldizenyl) benzaldehyde (1). The compound (1) has been treated with different substituted acetophenone to give a new series of chalcone derivatives 1-(substituted)-3-(2-((4-chlorobenzyl)oxy)-5-(m-tolyldiazenyl) phenyl) prop-2-en-1-one (2a-j). The chalcone derivatives have been treated with hydrazine hydrate according to Michael addition reaction to afford a series of new pyrazoline derivatives. The characterization of the newly synthesized compounds elucidated by FT-IR, 1H-NMR, 13C-NMR, 13C-DEPT and elemental analyses

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Published

2023-02-01

How to Cite

Ahmed A. ALKazmi, Farouq Emam Hawais, & Yuosra K. Alasadi. (2023). Synthesis and Characterization of some Pyrazoline derivatives from Chalcones containing azo and ether groups. Tikrit Journal of Pure Science, 22(9), 69–75. https://doi.org/10.25130/tjps.v22i9.877

Issue

Vol. 22 No. 9 (2017)

Section

Articles

License

Copyright (c) 2023 Tikrit Journal of Pure Science

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