Development of Spectrophotometric method for quantitative determination of dexamethasone in pharmaceutical preparations

Abstract

This Study is concerned a fast, easy, sensitive, accurate and economical spectrophotometric method for the determination of Dexamethasone. This method based on the use of UV- spectra measurements at 242 nm.

 The linearity of the method is performed between (3 - 65) μg.ml^-1, the  coefficient of  correlation was = 0.9998. The value of Rec% and RSD% are found at the range (95.28 -102.86)% and (0 - 0.272 )% respectively, The LOD and LOQ were (0.024and 0.081) μg.ml^-1, respectively .

The method was successfully applied to the determination of DMT in Bulk and pharmaceutical preparations