The physiological effect of breast cancer on activity of aromatase enzyme and some concentrations of hormones and biochemical in the women in Baghdad city

Abstract

This study was conducted to investigate the effect of women breast cancer on some hormones (Estrogen, Testosterone, prolactin) and biochemical parameters (Glucose, Cholesterol, Aromatase). The study is done in Medical City Teaching Hospital in Baghdad to show the effect of age, body weight and type of feeding for women with breast cancer and compared with healthy women. Their age ranged between (24-70) years for both groups. The results showing high significant effects of all parameters study in cancer disease women compared with healthy. All Study parameters increased with the advance of age and with the increased in body mass index. The breast cancer was spread in women artificial infant feeding compared with natural feeding .The conclusion suggested that the increase in estrogen, testosterone, prolactin, aromatase, cholesterol and glucose when the women have breast cancer.