Biochemical study of antioxidants level in saliva and serum of obese individuals who have a family history of type II diabetes mellitus

Abstract

The study includes a comparative study  biochemical  comparative study  between the blood and saliva at some pointers early diagnosis for diabetes type II in obese people and over weight ,as this study was conducted on 150 sample (males and females) of  blood serum and saliva ,as she was the first set of blood serum of fat people with over  weight and they have not family history of second type ΙΙ diabetes obese and over weight people have a family history of diabetes.                                                                                                                                       

The concentration of glucose was measured, glutathione, the effectiveness of the enzyme glutathione peroxidase, Catalase, malondialdehyde, peroxy nitrit nitrit peroxy, uric acid, total protein, albumin, triglycerides s, cholesterol, fat high_ density HDL_C, fat low -density LDL-C-very low fat density VLDL-C, the proportion of body mass index- BMI and age of each sample.                                              

Results indicated that the  presence of  artificial  increasing  in the level of glucose to blood serum and obese of fat people who are over wight and who have family history of diabetes they are comparred whith the control group, while the level of glutathione is high in the blood serum and there are no artificl  difference  in the saliva  enzayme glutathione the lack of artifical diffrence of plasma and the decline in the saliva of the enzyme catalase, high moral in the blood serum and no difference in the saliva of the level of dual malondialdehyde, an artifical increaing in blood serum and saliva to the level of peroxy nitrit, no signifigant diffrence in the serum of blood and decreasing in the saliva of he level of uric acid ,a significant increasing in blood serum and saliva decline in the level of total protein was observed ,no significant diffrence in blood serum and saliva decreasing in the level of albumin people who have a history of diabetes.

 the level of fat in the serum of blood and saliva (triglycerides, cholesterol, high_ density fat, low fat and very density) were studied among the groups .The results showed a significant increasing in serum blood, saliva tripal fat, cholesterol, fat low density, and very few fat density aggregates while there is no significant diffrence of fats serum high_ density and high in the saliva obese people have a family history of diabetes is. so observed .So these results are early diagnosis for diabetes type II in the blood serum and saliva of obese people who have a family history of diabetes.