Stady of Effect of Klebsiella pneumonia K- a ntigen as a immune catalyzer for laboratory rabbits infected with Entamoeba histolytica

Abstract

Conducted this study for the duration  from the December 2013 until November 2014. and our study have included  extrated capsular  polysaccharide (K-Antigen) from  Klepsiella pneumoniae and study  chireffection the immune response in Neusland albino rabbits(male) infected whith Entamoeba histolytica that cause  amoebic dysentery disease depending on several criteria, including study the changes in variables cytokineetics  concentration levels that response on phagocytosis and antigen presenting proscess like INF-Y, IL-10 and IL-12  and phagocytosis coefficienit, and B T cells PMNs and lymphocytes cell life span, the  T and B rossite formation test  the miotic index factor for bone marrow cell Arthus reaction, dilayed hypersensitivity, measure the humoral immune response that responsting by immunoglobulins  like IgG, IgM using ELISA Technic.

And The current study accessed to elevated all immuniyy indicator after immunization with (k) antigen and also continue in elavation after the infection with parasite,and we indicated from this study the possibility to use the capsular polysacchride (k antigen) that extracted from Klebsiella pneumoniae as immunological modificicatory that can stimulate both innate (natural)and acquiredimmunity agnest amoebic dysentery infection in white rabbite.