Study the Balance System Between Oxidants/Antioxidants in Patients with Peptic Ulcer in City of Tikrit and it's Suburb

Authors

  • Anfal Kadhim Noori
  • Sahib J. Abdoul rahman

DOI:

https://doi.org/10.25130/tjps.v20i1.1137

Abstract

This study aimed to find out the current role of free radical and oxidative stress in the events of this disease through the study the determined levels of lipid peroxidation and some of number  antioxidents concentrations. The study included (100) patients with Peptic ulcer (50 males and 50 females) as well as (50) people (25) healthy males, 25 females) as a control group.

(5) ml of blood from the Anticubital vein for the purpose of estimating the concentrations of  malondialdehyde (MDA( and peroxinitrate radical (ONOO.-) and some enzymic antioxidants such as catalase (CAT), superoxidismutase (SOD), glutathion peroxidase (G-px) ,and non- enzymic antioxidants such as glutathion (GSH), ceruloplasmin (CP), uric acid , albumin.

The results showed a significant increase (P≤0.01) in the concentration of the (MDA) and (ONOO.-) and a  significant decrease in the concentration of the (CAT), (SOD), (G-px) , (GSH), (CP), Uric acid, Albumin in the blood serum of patients with peptic ulcer males and females compared to the control group.

This study clear that the oxidative stress and free radicals a major role in the development of Peptic ulcer disease.

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Published

2023-02-08

How to Cite

Anfal Kadhim Noori, & Sahib J. Abdoul rahman. (2023). Study the Balance System Between Oxidants/Antioxidants in Patients with Peptic Ulcer in City of Tikrit and it’s Suburb. Tikrit Journal of Pure Science, 20(1), 63–70. https://doi.org/10.25130/tjps.v20i1.1137

Issue

Vol. 20 No. 1 (2015)

Section

Articles

License

Copyright (c) 2023 Tikrit Journal of Pure Science

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