Effect of the boiled cumin seeds extract in the glucose, some hormones concentration and aortic tissue in New Zealand white male rabbits fattened experimentally

Abstract

The present study was performed in Department of Biology/College of Science/University of Mosul to determine the effect of fattening New Zealand Albino male rabbits experimentally and use boiled cumin seeds extract in the glucose ,some hormones concentration and aortic tissue. It used 40 male from New Zealand albino rabbits and ages ranged from 10.8 months and weights ranging from 1400-1250gm,, divided into two groups of 20 rabbit / group and putted in separate cages. Fed  the first group to standard diet, while the second group fed special diet rich in fat for the purpose of fattening for a period of 12 weeks after a period all rabbits were weighted, and divided into four groups of 10 rabbit / group,  are control group,  Cumin group, fattening group and fattening with cumin: , all these groups underwent   standard condition of water and diet,, cumin group and group and fattening with cumin group dosing with2000 mg / kg body weight boiled cumin seeds extract for 8 weeks where a daily dosage.

The results showed that treatment with boiled cumin seeds extract may have led to a decrease in the concentration of glucose in each of cumin group and a fattening with cumin, while an event significant increase in the concentration of glucose in the fattening group, also showed occurrence of a significant decrease in the concentration of the insulin as compared to fattening , as well as the occurrence of significant increase in the concentration of each of the TSH , T3 and T4 hormones  in the all of group  treatment at boiled cumin seeds extract, while an event significant decrease of these hormones in fattening group as compared to control, as an improvement in the histological picture tissue aortic treatment boiled cumin seeds extracted.