Synthesis and Characterization of some 2,3-dihydroquinozoline and evaluation of their biological activity

Authors

  • Adil Hussein Dalaf
  • Fawzi Hameed Jumaa
  • Salwa Abdul-Satar Jabbar

DOI:

https://doi.org/10.25130/tjps.v23i8.545

Keywords:

Benzidine, Azo, Schiff's base, 2,3-Dihydroquinozoline

Abstract

This work included the synthesis of azo dye (A1) by the reaction of diazonium salt to benzidine with salicyldehyde at (0-5) oC  and synthesis of schiff base (A2-A6) through reaction substituted aromatic amine with aldehyde group in azo compound (A1) in ethanol compounds (A2-A6) and 2,3-dihydroquinozoline derivatives prepared by reaction schiff base with anthranilic acid in ethanol compounds (A7-A11), and characterization by using spectroscopic techniques Uv/Vis, FT-IR, C.H.N. and H1-NMR of some the prepared compounds using DMSO-d6 as a solvent, in addition to melting point and determination a purity of TLC, This work consisted a study of biological activity for some prepared compounds against four types of pathogenic bacteria to detect their resistance to anti biotic, drugs.

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Published

2018-08-08

How to Cite

Adil Hussein Dalaf, Fawzi Hameed Jumaa, & Salwa Abdul-Satar Jabbar. (2018). Synthesis and Characterization of some 2,3-dihydroquinozoline and evaluation of their biological activity. Tikrit Journal of Pure Science, 23(8), 66–76. https://doi.org/10.25130/tjps.v23i8.545

Issue

Vol. 23 No. 8 (2018)

Section

Articles

License

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