Tikrit Journal of Pure Science

Effect of Vitamin D deficiency and some hematological parameters in Iraqi female patients with Systemic Lupus Erythematosus

Ekhlass Noori Ali — 2024-08-25

Background: Systemic Lupus Erythematosus (SLE) is a chronic inflammatory autoimmune disease that affects multiple organs. Vitamin D deficiency is considered potential environmental factor triggering some autoimmune disorders, including SLE. This study was performed for determination of effect of vitamin D deficiency in SLE infection or disease worsening, and the relationship of ESR, HB, and WBCs with level of vitamin D in SLE disease, in addition to determine which of the previous parameter may describe the disease case of patients.

Methods: This study included fifty three (53) SLE female patients and twenty six (26) healthy females were included. White blood count (WBC) and Heamoglobin (Hb) were determined in complete blood count (CBC) device, traditional Westergren method was used for Erythrocyte sedimentation rate (ESR) estimation, vitamin D was measured by using enzyme link immune-sorbent assay (ELISA) Kit.

Results: The results showed a significant decrease in the hemoglobin levels in the SLE patients; significant increase was noticed in the ESR of SLE patients and significant increase was noticed in the WBC counts compared to the control group’s samples. A significant decrease in serum levels of vitamin D in patients compared to apparently healthy controls.

Conclusions: Photosensitivity to sun in SLE patients contributed in decrease of vitamin D blood-levels. According to the ROC results, each of Hb, WBC, ESR and vitamin D may describe the disease case of patients.

The relationship between the effect of panic attack and physiological parameters in some patients and animals lab

Sara Maziad Ali — 2024-08-25

The effects of a panic attack were studied in some patients who do not have hereditary diseases "sudden onset" as well as using laboratory animal "rats" to examine the types of effects on some physiological parameters. compared with control. These attacks affect daily life and result from a complex interaction between environmental, neurological, and psychological factors. Venous blood samples were collected from people suffering from non-genetic diseases. Blood samples were also collected from experimental animals exposed to fear at intervals of 0, 3, 7, and 28 days to detect the relationship between environmental factors and some physiological factors. Statistical analysis was performed using the SPSS program. The results indicated an increase in the level of cholesterol, glucose, and C-reactive protein in people with non-genetic diseases compared to their decrease in the control group, in addition to an increase in the level of cholesterol and glucose and no effect on C-reactive protein in rats exposed to the impact of fear and low body weight. The results also show a significant increase in heart and breathing rates and a significant decrease in oxygen levels.

Estimation of vitamin D status and calcium level among pregnant women in Tikrit city: case control study

Tafaoul Jaber AL Jubory — 2024-08-25

The demand for calcium and vitamin D rises during pregnancy, increasing the chance of hypocalcemia and vitamin D deficiency. Hypocalcemia may be associated with pregnancy-related complications. This study thus sought to ascertain the frequency of hypocalcemia and vitamin D insufficiency in pregnant women seeking secondary care, as well as to explore the possible associations between these disorders and pregnancy outcomes.

Subjects, Materials and method: This study was conducted without the use of vitamin D supplements in the first, second, and third trimesters at gestational ages more than 40 weeks, even before the convenience sample number 36 became pregnant. Control groups for Case number 10 non pregnant women. The age of cases and control women in range from 20-35years. Using the Roche Cobas e411 immunoassay device, we calculated the serum concentrations of calcium and vitamin D. The study carried out between December 2023 and February 2024 in Tikrit Teaching Hospital.

Results: A total of 36 pregnant women were enrolled in the study Mean (SD) serum Vitamin D level was 17.9±0.12mg/dl pregnant women with First trimester, 11.8± 0.18mg/dl pregnant women with second trimester and 10.5 ± 0.20mg/dl pregnant women with third trimester compared with control groups 44.4 ± 0.40 (p-value = <0.001). As well as Mean (SD) serum calcium level was (7.9±0.10, 8.2± 0.18, 7.5 ± 0.20 mg/dl) pregnant women with First, second and third trimester respectively, compared with control groups 8.4 ± 0.40 (p-value = 0.06).

The Study the Effect of Type and Duration of Treatment on Some Hematological and Biochemical Variables of Lymphoma Patients in Al-Muthanna Province, Iraq

Sarah Sakban Hasan — 2024-08-25

The term "malignant lymphoma" describes primary cancers of the lymphoreticular system, almost all of which begin as lymphocytes. This study aimed to assess the impact of therapy type and duration on several hematological and biochemical parameters in lymphoma patients. The study was conducted from July 2023 to October 2023. This study examined one hundred samples in total, fifty sample as control group and fifty sample as patients group. The age range of the participants was between 5 and 77 years old. Some hematological and biochemical tests were analyzed in the current study. The study showed a significant increase (P<0.05) according to type and duration of therapy in patient groups. The study indicated a significant decrease (P<0.05) in red blood cells(RBC), hemoglobin (Hb), lymphocyte and basophils compared with control groups, but indicated a significant increase (P<0.05) in white blood cells (WBC), neutrophils and platelets compared with control groups. Also, the study showed a significant increase (P<0.05) in urea, creatinine, alanine aminotransferase(ALT) and aspartate transaminase (AST) compared with control groups.

Analysis of the Synergistic Effect of Antibiotics with Copper Oxide Nanoparticles Against Pseudomonas aeruginosa Isolated from Different Clinical Cases

Rusl Ahmed Mahdi Saleh — 2024-08-25

Synergism between antibiotics and nanoparticles is one of the most important ways to combat antibiotic resistance. Copper nanoparticles were produced using a green, environmentally friendly method of mixing aqueous Ficus Sycomorus leaf extract with copper sulfate. The work aimed to study the synergistic effect of six antibiotics with copper oxide nanoparticles prepared in a green approach against bacteria Pseudomonas aeruginosa isolated from patient. A total of 110 specimens were collected from patients with burn, wound and urine infections. in Samarra General Hospital, Tikrit Teaching Hospital, Tikrit Military Hospital, and Baghdad Medical City of both genders from July to September 2023. A bacteriological examination was conducted to select bacterial pathogens, with a particular focus on Pseudomonas aeruginosa. From a total 110 cases, 50 (45.5%) gave positive cultures for Pseudomonas aeruginosa. CuO-NPs was characterized using different analytical techniques, Scanning Electron Microscope (SEM). showed that the CuO-NPs have a spherical shape, its average size is 29.2 nm. Energy-dispersive X-ray )EDX( results confirmed the presence of copper and oxygen in the composition. The synergistic effect of six antibiotics with CuO-NPs was studied. By evaluating the minimum inhibitory concentration of P. aeruginosa. The results show the highest inhibition against bacterial isolates was due to the synergistic effect of CuO-NPs with Impenem, Ciprofloxacin, Ceftazidime, Polymyxin B, Amikacin, and Cefepime respectively, especially on isolate (15) with zones of inhibition/mm were 19.33 ±0.33, 18.33 ±0.33, 16.33 ±0.33, 15.33 ±0.33, 14.67 ±0.33, and 12.7±0.58, respectively. The results indicated that the synergistic effect gave clear zones of inhibition against all isolates compared with the inhibition effect of nano-copper oxide and antibiotics.

Design and feed two models for microstrip antenna in two different feed methods and compare their properties

Ammar Mohammed — 2024-08-25

In any wireless communication, the antenna plays a very important role. The need in this technology is to reduce the size of the antenna, weight, and cost with a low profile, high performance, and low return loss (RL), which is what researchers are striving for. This paper attempts to implement a rectangular microstrip patch antenna and analyze its performance for different types of feeding techniques. In this research, we designed two thin slice antennas fed in two different ways, using FR4 epoxy as an insulating substrate with a dielectric constant of 4.3. Copper was used as a conducting material for the radiating patch and the transmission line, with nearly similar geometrical dimensions. The first antenna has dimensions of (31x 26x1.6) m3 and the second antenna has dimensions of (30x27x1.6) m3. The first antenna operates with a coaxial probe feed technique and the second one operates with a microstrip line feed technique. The return loss for the first antenna we obtained is -26.0113dB with a standing wave voltage ratio of 1.1053 at a frequency of 3.59GHz, and -24.743GHz with a standing wave voltage ratio of 1.8908 at a frequency of 5.529GHz. The return loss for the second antenna is -27.468dB with a standing wave voltage ratio of 1.0884 at a frequency of 3.45GHz. The design, simulation, and inclusion of shapes and graphics for both antennas were done using the CST (Computer Simulation Tool) program

Optimizing Fractional Differential Equation Solutions with Novel Müntz Space Basis Functions

Asrin shekh — 2024-08-25

This paper introduces innovative basis functions derived from Müntz spaces, aimed at addressing the computational challenges of Fractional Differential Equations (FDEs). Our primary focus is the creation of these functions using singular indices linked to the solutions of FDEs. We thoroughly investigate the properties of these fundamental functions to understand their operational potential. These functions are particularly adept at capturing initial singular indices, making them highly suitable for solving FDEs. The proposed numerical method is distinguished by its rapid convergence rates, showcasing its efficiency in computational evaluations. We validate our approach by presenting numerical examples that highlight its accuracy and reliability. These examples confirm the effectiveness and efficiency of the new basis functions from Müntz spaces in accurately solving FDEs. This research advances numerical methods for FDEs and serves as a valuable resource for researchers seeking robust and reliable techniques