Follow-up some tissue changes in infected mice Balb/C experimentally with Trichomonas muris and treated with extracts of Artemisia herba-alba and Metronidazole drug
DOI:
https://doi.org/10.25130/tjps.v21i2.971Abstract
The present study was included investigation efficiency of alcoholic and aqueous extract of Artemisia herba-alba in treatment of albino mice infected experimentally with T. muris comparative with metronidazole drug. The doses of alcoholic and aqueous extracts of A. herba-alba for treatment were 750 mg/ kg as a single treatedable dose and then done comparable between efficiency of extracts under study and Metronidazole drug that given as a single dose of 0.392 mg/ mouse/day.
The results of this study revealed efficiency of both metronidazole drug and extracts of A. herba-alba in treatment the infected with T. muris. So these were treated with materials revealed effective and efficiency in treatment (100%), but it were different in the time for reduction of infection and perfect cure. Also the effect investigated of alcoholic and aqueous extract of Artemisia herba-alba and metronidazole drug in intestinal (ileum and colon) and liver, where observed normal form of intestinal and liver tissues of infected mice that treated with alcoholic and aqueous extract of Artemisia herba-alba and metronidazole drug, while observed abnormal form of intestinal and liver tissues of infected mice (positive control) and not treated with alcoholic and aqueous extract of Artemisia herba-alba and metronidazole drug.
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