Isolation and Identification of Some Dermatophytes and study its sensitivity to antifungal and Ago, Zno nanoparticles
DOI:
https://doi.org/10.25130/tjps.v26i5.174Abstract
This study aimed to determine the main species of dermatophytes which caused skin infection and effect of antifungal and Ago and Zno nanoparticles on them. The result of this study showed that out of 80 sample, 54 sample were positive to fungal isolation with ratio 67.5%, male 72.0% and female 62.1% the results show that’s highest infection case was Tinea Capitis with ratio 26.2% and lowest was Tinea cruris with ratio 2.5% , according to culture and PCR results 38.8% of isolated type belong to Trichophyton mentagrophytes and 3.7% of Epidermophyton floccosum .
Trichophyton mentagrophytes resistant to Nystatin and Fluconazole while sensitive to Griesofulvin, Clotrimazole and Flucytosin. MIC of Ago and Zno nanoparticle against Trichophyton mentagrophytes were 250 and 275 μg /ml while MFC were 275 and 300 μg /ml respectively. Results of RAPD PCR showed that both Ago and Zno nanoparticle effect in genetic material which showed as appear or disappear in thickness of bands of Trichophyton mentagrophytes .
Downloads
Published
How to Cite
License
Copyright (c) 2022 Tikrit Journal of Pure Science
This work is licensed under a Creative Commons Attribution 4.0 International License.
Tikrit Journal of Pure Science is licensed under the Creative Commons Attribution 4.0 International License, which allows users to copy, create extracts, abstracts, and new works from the article, alter and revise the article, and make commercial use of the article (including reuse and/or resale of the article by commercial entities), provided the user gives appropriate credit (with a link to the formal publication through the relevant DOI), provides a link to the license, indicates if changes were made, and the licensor is not represented as endorsing the use made of the work. The authors hold the copyright for their published work on the Tikrit J. Pure Sci. website, while Tikrit J. Pure Sci. is responsible for appreciate citation of their work, which is released under CC-BY-4.0, enabling the unrestricted use, distribution, and reproduction of an article in any medium, provided that the original work is properly cited.
