New Pyrazolines with Imine Moiety: Synthesis, Characterization

  • Marwa A. Atiyah
  • Olfat A. Nief
  • Abdulkader M. Noori

Abstract

Chalcone was prepared  by   claisen- schmidt  condensation  between   reaction equivalent moles  from 4-amino acetophenone with  thiophen -2-carboxaldehyde in presence sodium hydroxide as base, the mechanism was involved the abstraction α Proton by base from the α-carbon of the ketone to form carbanion, which attacks carbonyl of aldehyde contains no α-hydrogens to produce α-β-unsaturated ketone, Chalcone derivative used to synthesize pyrazoline derivatives by condensation with 2,4-dinitro phenyl hydrazine. The newly synthesized compounds were determined using spectroscopic methods such as FTIR, Mass spectra, 1H-NMR


 


http://dx.doi.org/10.25130/tjps.26.2021.077  

Published
Nov 21, 2021
How to Cite
ATIYAH, Marwa A.; NIEF, Olfat A.; NOORI, Abdulkader M.. New Pyrazolines with Imine Moiety: Synthesis, Characterization. Tikrit Journal of Pure Science, [S.l.], v. 26, n. 5, p. 40-47, nov. 2021. ISSN 2415-1726. Available at: <https://tjps.tu.edu.iq/index.php/j/article/view/1198>. Date accessed: 08 dec. 2021. doi: http://dx.doi.org/10.25130/j.v26i5.1198.
Section
Articles