Estimation of vitamin D status and calcium level among pregnant women in Tikrit city: case control study

Abstract

The demand for calcium and vitamin D rises during pregnancy, increasing the chance of hypocalcemia and vitamin D deficiency. Hypocalcemia may be associated with pregnancy-related complications. This study thus sought to ascertain the frequency of hypocalcemia and vitamin D insufficiency in pregnant women seeking secondary care, as well as to explore the possible associations between these disorders and pregnancy outcomes.

Subjects, Materials and method: This study was conducted without the use of vitamin D supplements in the first, second, and third trimesters at gestational ages more than 40 weeks, even before the convenience sample number 36 became pregnant. Control groups for Case number 10 non pregnant women. The age of cases and control women in range from 20-35years. Using the Roche Cobas e411 immunoassay device, we calculated the serum concentrations of calcium and vitamin D. The study carried out between December 2023 and February 2024 in Tikrit Teaching Hospital.

Results: A total of 36 pregnant women were enrolled in the study Mean (SD) serum Vitamin D level was 17.9±0.12mg/dl pregnant women with First trimester, 11.8± 0.18mg/dl pregnant women with second trimester and 10.5 ± 0.20mg/dl pregnant women with third trimester compared with control groups 44.4 ± 0.40 (p-value = <0.001). As well as Mean (SD) serum calcium level was (7.9±0.10, 8.2± 0.18, 7.5 ± 0.20 mg/dl) pregnant women with First, second and third trimester respectively, compared with control groups 8.4 ± 0.40 (p-value = 0.06).