Study Some Virulence Factors of CO- agulase Positive Staphylococci and CO-agulase Negative Staphylococci Isolated from Different Parts of Human Body

Abstract

This study included test production of some virulence factors that product from some species of Staphylococci: Co- agulase Positive Staphylococci (COPS) and Co-agulase Negative Staphylococci (CONS) that isolated from different parts of human body. (79%) of isolates was COPS while (21%) was CONS. All isolates showed production some virulence factors like (Protease, DNase, Lipase, Licithinase and Haemolysin) and the results were in COPS (64, 64, 55, 55 and 100)% respectively while all isolates of CONS were produced all this virulence factors except the licthinase . The results of all isolate were positive for oxidase test and negative for catalase test. From the results about (36.3%) of COPS produce white pigment and (63.6%) produced yellow pigment while all isolates of CONS was produced white pigment. Also the results showed that (86% and 71%) COPS isolates was produced haemolysine enzyme type (β and γ) while (14% and 29%) of CONS produced same enzyme type. Antibiotic susceptibility of all isolates were done,the results showed that all  CONS isolates were Susceptible towards (Amikacin, Tobramycin, Tetraccline, Nitrofurantoin, Chloramphenicol and Clarithromycin) antibiotics but  (33.3%) of CONS isolates were showed susceptible towards (Ampicillin, Amoxicillin, Cefdinir and Vancomycin) antibiotics. While in the COPS isolates showed low susceptibility rate towards (Vancomycin, Tetracycline Amikacin and Tobramycin) antibiotics  and in different percentage (81.8, 54.5 and 90.9)% respectively while (42.8,36.3, 9, 18.1, and 45.5)% were susceptible to (Ampicillin, Cfidor, Pencillin, Amoxicillin, Ticarcillin-clavulanic acid, Tobramycin, Cephalothin, Erythromycin, Chloramphenicol and Clarithromycin) respectively.

In conclusion, all isolates which have high resistance to antibiotics have low susceptible to same antibiotics.