Synthesis and Characterization of some 2,3-dihydroquinozoline and evaluation of their biological activity

  • Adil Hussein Dalaf
  • Fawzi Hameed Jumaa
  • Salwa Abdul-Satar Jabbar

Abstract

This work included the synthesis of azo dye (A1) by the reaction of diazonium salt to benzidine with salicyldehyde at (0-5) oC  and synthesis of schiff base (A2-A6) through reaction substituted aromatic amine with aldehyde group in azo compound (A1) in ethanol compounds (A2-A6) and 2,3-dihydroquinozoline derivatives prepared by reaction schiff base with anthranilic acid in ethanol compounds (A7-A11), and characterization by using spectroscopic techniques Uv/Vis, FT-IR, C.H.N. and H1-NMR of some the prepared compounds using DMSO-d6 as a solvent, in addition to melting point and determination a purity of TLC, This work consisted a study of biological activity for some prepared compounds against four types of pathogenic bacteria to detect their resistance to anti biotic, drugs.


http://dx.doi.org/10.25130/tjps.23.2018.131  


 


 

Published
Aug 8, 2018
How to Cite
DALAF, Adil Hussein; JUMAA, Fawzi Hameed; JABBAR, Salwa Abdul-Satar. Synthesis and Characterization of some 2,3-dihydroquinozoline and evaluation of their biological activity. Tikrit Journal of Pure Science, [S.l.], v. 23, n. 8, p. 66-76, aug. 2018. ISSN 2415-1726. Available at: <http://tjps.tu.edu.iq/index.php/j/article/view/151>. Date accessed: 26 nov. 2019.
Citation Formats
Issue
Vol 23 No 8 (2018)
Section
Articles